Thursday, February 28, 2013

DARPA trying again to develop a high-speed VTOL aircraft

DARPA trying again to develop a highspeed VTOL aircraft

If at first your unmanned aerial vehicles don't succeed... try, try again? After a series of unsuccessful tests with the Boeing X-50 Dragonfly and Groen Heliplane, the US government is once again trying to develop a high-speed, vertical takeoff-and-landing (VTOL) aircraft. DARPA just announced the VTOL X-Plane program, a 52-month, $130 million project with one mission: to build an aircraft that can exceed 300 knots, achieve a hover efficiency of 75 percent or better, and hit a cruise lift-to-drag ratio of 10 or more.

In layman's terms, such an aircraft would be faster than a traditional helicopter, but still have better hover efficiency than a modern high-speed 'copter. Sounds like a sensible idea, right? The thing is, DARPA doesn't know yet how such a thing would look: for now, the agency is merely soliciting proposals, with a particular emphasis on smaller, non-traditional companies nimble enough to develop products quickly. So if you've got any good ideas, may as well head on over to the source link, we guess, and try your luck.

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Via: Defensetech

Source: Federal Business Opportunities

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Indonesia finance minister says not being pushed out of job

JAKARTA (Reuters) - Indonesia's finance minister denied on Thursday that he was being pushed out his job, dismissing speculation that he was being shifted to the post of central bank governor because he had crossed swords with politically powerful businessmen.

President Susilo Bambang Yudhoyono last week unexpectedly nominated Finance Minister Agus Martowardojo to replace Darmin Nasution, whose term as Bank Indonesia governor ends in May.

There has been no clear explanation from the presidential palace why either man is moving from his current job, nor who would be the new finance minister if Martowardojo is approved by parliament to head Bank Indonesia.

Members of parliament will debate Martowardojo's candidacy later next month, and some have questioned his suitability for the job.

Asked if he had been the victim of vested political or business interests, the finance minister said "No".

"(There was) no political pressure," Martowardojo told reporters on the sidelines of a conference. "It is an honor to be nominated as central bank governor."

FOR AND AGAINST

Earlier, Vice President Boediono, himself a former central bank governor, told Reuters that Bank Indonesia needed a safe pair of hands to replace the outgoing governor.

Martowardojo, 57, took over as finance minister in 2010 to oversee one of the world's fastest growing economies and before that headed the biggest state-controlled bank, Bank Mandiri.

The uncertainty over who will lead Bank Indonesia has caused little concern in the financial markets. Indonesia's benchmark stock index is set to close at a record high for the second consecutive day, up 1.3 percent at 4,777.86 in late trading on Thursday.

A parliamentary commission has the final say over who heads the central bank. One commission member said Martowardojo, a career banker, lacked macro-economic expertise and another that there were doubts over his integrity.

But the chairman of the commission, Emir Moeis, has said he was in favor of the finance minister's switch to the central bank.

There has been speculation that Martowardojo was being pushed from the cabinet because of his very public opposition to two major issues involving influential businessmen.

One relates to his insistence that the central government buy a stake in a gold mining company, an issue which involves the Bakrie family. One of the Bakrie brothers is the Golkar Party's presidential candidate.

Another concerns a project to build a bridge linking the islands of Java and Sumatra. Martowardojo has opposed the project, which is headed by wealthy businessman Tommy Winata, in its current form.

(Reporting by Neil Chatterjee; Writing by Randy Fabi and Jonathan Thatcher; Editing by Simon Cameron-Moore)

Source: http://news.yahoo.com/indonesia-finance-minister-says-no-political-pressure-oust-063958270--business.html

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HTC's 'Tiara' crowns a medium spec, Windows Phone 8 GDR2 device

HTC's 'Tiara' crowns a medium spec, Windows Phone 8 GDR2 device

Trust. It's a valuable commodity. But serial twitter-sleuth evleaks has done enough to earn ours for this latest leak. A Windows Phone 8 device -- apparently known internally as the Tiara -- which will be one of the first to run the next revision of the mobile operating system (GDR2). With a reported 4.3-inch display, a 1.2GHz Snapdragon processor, 1.6-megapixel front-facing camera and 1GB of RAM, it bears more than a resemblance to another recent addition to the HTC fold. If you had hopes that it might also borrow from the firm's latest Android flagship design, then sorry to dash them, as the sources suggest otherwise. The Tiara moniker is unlikely to remain, with evleaks taking a stab at it coming to market mid-May, possibly as the HTC 8W. Not a bad guess. Now it's just a matter of waiting to see if all that trust is truly well placed.

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Source: Unwired View

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Google Glass is an all-knowing virtual assistant ? is your head ready?

You may have recently spotted some goofy-looking headgear gracing the brows of the Google founders ? and a few supermodels, too. While it may seem like a cyberpunk fashion statement that just got too literal, Google's Project Glass, a wearable camera/display combo, may well be the future of human-machine interaction.

"One thing that we're really excited about and working hard on is transforming the way that people interact with Google," said Scott Huffman, Google's vice president of engineering for Search, showing off a video demonstrating the search engine giant's new sensation. "From the stilted one-keyword-at-a-time conversation, to more of a natural conversation ? like a human assistant."

Make no mistake, Huffman isn't talking about a virtual assistant along the lines of Apple's Siri, which responds to your questions. He's talking about a way to interact with a search engine ? and all its associated products ? that includes it gathering so much data about your life and habits, it will start anticipating your needs. Cool? Yes. Creepy? Maybe that, too.

"If you think about a good assistant," Huffman told me, pausing to correct himself, "a great assistant ? they don't interrupt you every few minutes." He described his own assistant, someone who doesn't interrupt him often, but certainly knows when she should give him a gentle reminder or a sharp kick.

"It's the opposite of the experience on your phone today," Huffman pointed out, referencing how disruptive our smartphones can be. Not only are they not capable of prioritizing our notifications, but they're mostly incapable of anticipating how the priorities themselves change depending on where we are ? or what time it is.

Though Google's improved experience will span all manner of devices ? "We're trying to think of it as ... your assistant is ubiquitously with you," said Huffman ? it's Google Glass that has everyone talking.

Under development in the Google X Lab ? that mysterious skunkworks where self-driving cars, neural networks, and other quirky yet ambitious projects are being dreamed up ? Glass is the most provocative way in which this assistant, your main touchpoint with Google, might interact with you.

A small display lives on a frame that resembles eyeglasses. It is connected to a camera, microphone, bone-conducting speaker, and more. Thanks to Wi-Fi and Bluetooth support, the device communicates with other gadgets, such as your smartphone, as well as the good ol' Web.

"OK, Glass!" ? with a command like that, you can prompt the device to take pictures, record video, initiate video chats, provide directions, send messages, search, translate and more. Cards resembling those seen in Google Now ? Google's response to Apple's Siri ? may occasionally appear in the tiny display, meant to remind you of a dentist appointment, provide updates on an upcoming flight, and so on.

A concept video released by Google about a year ago left some people under the misconception that Glass provides an augmented reality experience, where information is overlaid across a field of vision. Instead, as a new demo video confirms, Glass is significantly less disruptive. You actually have to glance up at the display.

Google's intent with Glass is to provide you with all the information you need, before you even think of a question, but without being a nag. Sound too crazy? Not for Google, says ... Google.

What people want ... and what they don't know they want
"Our role is to understand user needs in terms of our search products and make sure that we're developing a search experience that meets and exceeds expectations," Jon Wiley, Google's lead user experience designer for Search, told me in mid-December. To get a sense of how that was going, Wiley said, the company conducted a little human-nature study.

Wiley's team gathered up a group of folks "from all walks of life" and installed specialized software on their mobile devices. Throughout the day, this software prompted the study participants with a very open-ended question: "What was the last bit of information you needed?" The point of the study wasn't to trace the flow of data through the participants' handsets. Wiley's team just wanted to know what sort of information ? simple or complicated, mundane or exciting ? people were hunting for at any given moment.

The study not only allowed Wiley's team to better capture the sorts of queries that people don't ask a search engine ? "Why is my daughter being mean to me?" ? but also the context in which all these questions arose. Where were people when they needed to know these things? What time was it? What were they doing? By gathering these details, the team could attempt to understand the contexts of searches (even the helpless ones) in our day-to-day, human trudge.

One day, Google could perhaps provide all that information without prompting. After all, a diligent user of Google Now already gets flight information, traffic alerts, and other details automatically ? just based on itineraries, daily travel patterns, etc. But with Glass that information could always be front-and-center at the very moment it's needed. What if you're late for a flight? Checking for its gate information by reaching for a boarding pass, pulling your phone out of your pocket, or finding an airport information board wastes precious seconds. Glass could put the information right in front of you without delay.

The more information we share with Google, even just so that Google can better understand our data needs, the more privacy concerns will be raised. Google is already no stranger to privacy lawsuits and legislation, so how much more heated will things get when the company introduces eyeglasses that know as much ? or more ? about you than you know yourself?

Perhaps even more importantly, Google Glass is one of the first digital technologies capable of recording the world around you constantly: Will that cause discomfort for others? Will they start to avoid you once you're wearing a device that allows you to take photos or record video without even the slightest warning? And when will Google Glass data be brought into the courtroom for a divorce case, a robbery, or worse?

Despite its magical promises (and ominous portents), Google's creation may remain out of reach for a while ? until late 2013, at the very earliest. Google's currently only allowing select individuals to participate in the Google Glass Explorer program. This first publicly available Glass edition costs $1,500, and comes with an invite to a special pick-up event and more. In order to be part of the Glass Explorer program, you had to pre-order during Google I/O 2012 conference last June or make it through the recently announced #IfIHadGlass application process.

Nerd alert!
While the general public waits for the latest Google gadget to become available though, there's been plenty of criticism of Glass' appearance ? "these specs look like the freaky science fiction concept they are," Gizmodo's Mario Aguilar declared.

And the behoodied Mark Zuckerberg of Facebook, not exactly a fashion icon himself, is among those concerned about how he'll look wearing Glass on his face, reports Ryan Mac. The Forbes' writer witnessed an exchange between Zuckerberg and Google co-founder Sergey Brin after an event at the University of California on Wednesday.

"How do you look out from this without looking awkward?" Zuckerberg reportedly asked. "You know, how are you supposed to use these this without breaking eye contact?" (Neither Facebook nor Google chose to confirm that this conversation occurred.)

Still, Google seems to be working hard to ditch the belief that only the nerdiest of nerds will don Glass. The New York Times' Claire Cain Miller reports that Google may be in negotiations with eyewear seller Warby Parker "to help it design more fashionable frames" for Glass.

The company also collaborated with designer Diane von Furstenberg during last year's New York Fashion Week and brought Glass onto the runway.

?I am so excited to introduce Glass to the fashion world and use this revolutionary technology to give everyone a unique perspective into fashion," von Furstenberg was quoted as remarking, while Google co-founder Sergey Brin added that "beauty, style and comfort are as important to Glass as the latest technology."

Until Glass is publicly available ? and until we discover whether this groundbreaking virtual personal assistant is worth bending a fashion rule or two ? the last words on the subject go to actor LeVar Burton. Speaking for Geordi La Forge, a character he played in "Star Trek: The Next Generation," Burton tweets: "#ifihadglass It would be a downgrade."

Want more tech news or interesting links? You'll get plenty of both if you keep up with Rosa Golijan, the writer of this post, by following her on Twitter, subscribing to her Facebook posts, or circling her on Google+.

Source: http://www.nbcnews.com/technology/technolog/google-glass-all-knowing-virtual-assistant-your-head-ready-1C8479651

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Wednesday, February 27, 2013

Recommendation on Boeing 787s expected next week

WASHINGTON (AP) ? Experts at the Federal Aviation Administration are expected to say next week whether they recommend accepting Boeing's plan to fix its troubled 787 Dreamliners so the planes can resume flying, the agency head said Wednesday.

Officials in the FAA office near Seattle that certifies new planes as safe for flight are reviewing a Boeing proposal to revamp the 787's lithium ion batteries to prevent them from catching fire, or to protect the plane in case of fire, Administrator Michael Huerta said.

Huerta declined to say when he might decide whether to accept the plan or how long it might be before the planes are back in the air.

Boeing officials presented the plan to Huerta last week.

The planes have been grounded since Jan. 16 after a battery caught fire in a 787 parked at Boston's Logan International Airport and a smoking battery in a different 787 forced an emergency landing in Japan.

Calling the plan "very comprehensive," Huerta said Boeing engineers worked with outside experts to narrow the potential causes of the incidents to a few possibilities, and then redesigned the batteries. The 787 has two identical 32-volt batteries, each with eight cells.

Investigators have said the incidents began with short-circuiting in a single cell, leading to a chemical reaction that causes progressively hotter temperatures. That spread the short-circuiting and fire to other cells.

Boeing's plan includes redesigning the batteries to prevent individual cells from catching fire, Huerta said. Should that fail, the plan includes steps to prevent a fire from spreading to other cells or outside the box that contains all eight of the cells.

"What Boeing has assembled is a team to look at the universe of potential causes, and their proposal is to mitigate all of them," Huerta said.

If the plan is approved, the next step would be extensive engineering and testing before any final determination could be made on resuming flights, he said. He described the process as "effectively a certification plan."

"We have to be assured that this is a good plan and that it is going to result in a safe situation," Huerta said.

___

Follow Joan Lowy at http://www.twitter.com/AP_Joan_Lowy

Source: http://news.yahoo.com/recommendation-boeing-787s-expected-next-week-190620188--finance.html

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Gun control supporter backed by New York mayor wins Chicago vote

CHICAGO (Reuters) - Gun control supporter Robin Kelly won the Democratic primary for a Chicago area U.S. House seat on Tuesday, propelled by more than $2 million in television ads highlighting the guns issue bankrolled by New York Mayor Michael Bloomberg.

Kelly, a former Illinois state representative, said in her victory speech that the vote was a setback for the powerful gun rights lobby, the National Rifle Association.

"The voters sent a message that tells the NRA that their days of holding our country hostage are coming to an end. And their days of scaring Congress into submission on gun control are coming to a close," Kelly said to cheers from supporters.

The NRA fiercely defends the Second Amendment to the U.S. Constitution setting out the right to bear arms.

The Chicago special election was the first U.S. electoral test since gun control rose to the top of the political agenda after a gunman killed 26 people at an elementary school in Newtown, Connecticut, in December.

Since that massacre, which took the lives of 20 school children, President Barack Obama has pushed Congress to pass tighter gun restrictions and Bloomberg has vowed to use some of his fortune to help battle the political influence of the NRA.

The special election was to fill the seat of indicted former U.S. Representative Jesse Jackson Jr, who resigned in November citing health problems and pleaded guilty in federal court last week to using campaign funds for personal enrichment.

Jackson was a reliable vote in Congress for gun control. Until Bloomberg elbowed into the race, polls had shown that the special election might be won by Debbie Halvorson, a former congresswoman who had an A+ rating from the NRA and opposed an assault weapons ban.

Bloomberg blanketed Chicago television with ads on the gun issue, attacking Halvorson and endorsing Kelly in the final days of the campaign.

"He turned this election into a referendum on the NRA," said Chicago Democratic political analyst Don Rose.

A little over an hour after the polls closed, Halvorson called Kelly to concede defeat, saying that Bloomberg's television ads had overwhelmed her campaign.

"There was $2.3 million minimum spent against me," Halvorson told supporters. "That's the way it is. I can't help it."

The Illinois affiliate of the NRA had asked its members to vote for Halvorson.

Kelly, 56, highlighted Chicago's rash of murders from a surge in gang violence ravaging poor neighborhoods. The shootings have claimed the lives of dozens of young people, including Hadiya Pendleton, a high school student who was killed just over a week after she performed at Obama's inauguration.

Bloomberg issued a statement immediately after Kelly was declared the winner, saying that the Illinois vote showed Americans want change in Washington.

"As Congress considers the president's gun package, voters in Illinois have sent a clear message: We need common sense gun legislation now. Now it's up to Washington to act," he said.

Political analyst Rose said the Chicago district was receptive to Bloomberg's anti-gun message because it is heavily Democratic, and because of the plague of local gun violence. He said it was too soon to tell if the outcome would have national implications.

With nearly all the vote counted, Kelly had about 52 percent to 24 percent for Halvorson. More than a dozen other candidates, some of whom had withdrawn from the race but remained on the ballot, split the remainder of the Democratic vote.

Turnout was light because of a snowstorm that hit the Chicago area on Tuesday, making travel treacherous.

The winner of the Democratic primary is likely to be elected to the seat in the general election on April 9 because the district is Democratic. Three candidates were in a close race for the Republican nomination to face Kelly in April.

(Writing by Greg McCune, editing by Doina Chiacu)

Source: http://news.yahoo.com/gun-control-supporter-wins-chicago-house-primary-021434104.html

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Tribune hires advisers to field newspaper bids

(AP) ? Tribune Co. says it has hired investment banks JPMorgan Chase & Co. and Evercore Partners to help it sell its newspapers, which include the Chicago Tribune and Los Angeles Times.

The move comes two months after the media conglomerate emerged from bankruptcy.

Tribune spokesman Gary Weitman said the company has received "a lot of interest" in its newspapers. Hiring the firms, he said, will help Tribune Co. determine whether a potential buyer's interest is credible and assist the company in considering its options.

The sale of the newspapers has been widely expected, especially after the company appointed a group of TV-focused board members and hired former Discovery Communications chief operating officer Peter Liguori as its CEO last month.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-02-26-Tribune-Newspapers/id-28aa6bf975cb48069fe847f90816f4b1

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Tuesday, February 26, 2013

Why Rand Paul pulled a 180 in Hagel vote

Kentucky Sen. Rand Paul, left, stands next to Arizona Sen. John McCain. (Brendan Hoffman/Getty Images)

Only four Republicans crossed party lines on Tuesday to approve President Barack Obama's defense secretary nominee Chuck Hagel, but no senator sparked more confusion than Kentucky's Rand Paul, a vocal critic of Hagel who nonetheless cast his vote in favor of the former Nebraska senator.

Just hours after he had voted against a procedural measure to end debate over Hagel's nomination, Paul offered his support for Hagel's confirmation. Paul's spokeswoman explained that the senator decided to support Hagel because he believes that presidents should get "some leeway" on political appointments, an opinion he has been open about in the past.

"In the run-up to tonight?s vote to confirm former Sen. Hagel as secretary of defense, Sen. Paul voted twice against cloture on the nomination, because he agreed with many of his colleagues that there were questions that needed to be answered about the president?s nominee," Paul spokeswoman Moira Bagley told Yahoo News. "As he has said before, the president should be entitled to some leeway on his political appointments. That is why Sen. Paul voted in favor of Sen. John Kerry, with whom he largely disagrees on foreign policy, to serve as secretary of state, and that is why he voted for final passage of the nomination of Sen. Hagel this evening, with whom he also disagrees on a number of issues."

The Senate voted 58-41 to confirm Hagel, ending a long and contentious nomination process. The other Republicans who supported Hagel were Sens. Thad Cochran of Mississippi, Mike Johanns of Nebraska and Richard Shelby of Alabama.

Source: http://news.yahoo.com/blogs/ticket/why-rand-paul-voted-confirm-chuck-hagel-defense-232124614--politics.html

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U of M researchers identify genetic variation behind acute myeloid leukemia treatment success

U of M researchers identify genetic variation behind acute myeloid leukemia treatment success [ Back to EurekAlert! ] Public release date: 26-Feb-2013
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Contact: Amy Leslie
johns423@umn.edu
612-624-7654
University of Minnesota Academic Health Center

MINNEAPOLIS/ST. PAUL (February 26, 2013) Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.

Their study is published today in Clinical Cancer Research.

In the latest study, U of M researchers evaluated how inherited genetic polymorphisms in CD33, a protein that naturally occurs in most leukemia cells, could affect clinical outcomes of patients treated with an existing chemotherapy drug, gemtuzumab ozogamicin (GO), an immuno-conjugate between anti-CD33 antibody and a cytotoxin known as calicheamicin, which binds to CD33 on leukemic cells. As GO is internalized by leukemia cells, the cytotoxin is released, causing DNA damage and generating leukemic cell death.

In recent clinical trials GO has been shown to induce remission and improve survival in subset of patients with AML, however there is wide inter-patient variation in response.

Jatinder Lamba, Ph.D., and colleagues identified and evaluated three genetic variations of CD33 in two groups of patients with pediatric AML one group that received the drug GO, and one group that did not. They found that specific genetic variation in CD33 that significantly affected the clinical outcome of AML patients who received GO based chemotherapy.

"Understanding how genetics play a role in how drugs work is extremely useful, particularly for a drug like GO which has shown a very heterogeneous response in AML patients," said Jatinder Lamba, Ph.D., the study's lead author and a researcher who holds appointments in both the College of Pharmacy and the Masonic Cancer Center, University of Minnesota. "Our latest findings lead us to believe that genetic variation in CD33 influences how AML patients' leukemic cell responds to GO."

AML is a cancer of the blood and bone marrow, and is the second most common form of leukemia in children. Though the most common type of treatment for AML is chemotherapy, Lamba says the disease remains hard to treat and newer, more effective therapies are needed.

"The overall goal of our study was to use genetic data to predict beneficial or adverse response to a specific drug, thus opening up opportunities to use this information for drug optimization to achieve maximum therapeutic efficacy and minimum toxicity. Our hope is that our research could serve as a marker of prognostic significance for clinicians to select the therapy that has the greatest odds of being effective for individual patients based on their CD33 genotype."

###

Other University of Minnesota researchers involved in the study include Leslie Mortland, M.D., from the University of Minnesota Medical School and Betsy Hirsch, Ph.D., from the Medical School and the Masonic Cancer Center, University of Minnesota.

The University of Minnesota College of Pharmacy, the only school of pharmacy in Minnesota, offers its program on the Twin Cities and Duluth campuses. Founded in 1892, the College of Pharmacy educates pharmacists and scientists and engages in research and practice to improve the health of the people of Minnesota and society. The college is part of the Academic Health Center, which is home to the University of Minnesota's six health professional schools and colleges as well as several health-related centers and institutes. Learn more at www.pharmacy.umn.edu.

The University of Minnesota Medical School, with its two campuses in the Twin Cities and Duluth, is a leading educator of the next generation of physicians. Our graduates and the school's 3,800 faculty physicians and scientists advance patient care, discover biomedical research breakthroughs with more than $180 million in sponsored research annually, and enhance health through world-class patient care for the state of Minnesota and beyond. Visit www.med.umn.edu to learn more.

Masonic Cancer Center, University of Minnesota is part of the University's Academic Health Center. It is designated by the National Cancer Institute as a Comprehensive Cancer Center. For more information about the Masonic Cancer Center, visit www.cancer.umn.edu or call 612-624-2620.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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U of M researchers identify genetic variation behind acute myeloid leukemia treatment success [ Back to EurekAlert! ] Public release date: 26-Feb-2013
[ | E-mail | Share Share ]

Contact: Amy Leslie
johns423@umn.edu
612-624-7654
University of Minnesota Academic Health Center

MINNEAPOLIS/ST. PAUL (February 26, 2013) Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.

Their study is published today in Clinical Cancer Research.

In the latest study, U of M researchers evaluated how inherited genetic polymorphisms in CD33, a protein that naturally occurs in most leukemia cells, could affect clinical outcomes of patients treated with an existing chemotherapy drug, gemtuzumab ozogamicin (GO), an immuno-conjugate between anti-CD33 antibody and a cytotoxin known as calicheamicin, which binds to CD33 on leukemic cells. As GO is internalized by leukemia cells, the cytotoxin is released, causing DNA damage and generating leukemic cell death.

In recent clinical trials GO has been shown to induce remission and improve survival in subset of patients with AML, however there is wide inter-patient variation in response.

Jatinder Lamba, Ph.D., and colleagues identified and evaluated three genetic variations of CD33 in two groups of patients with pediatric AML one group that received the drug GO, and one group that did not. They found that specific genetic variation in CD33 that significantly affected the clinical outcome of AML patients who received GO based chemotherapy.

"Understanding how genetics play a role in how drugs work is extremely useful, particularly for a drug like GO which has shown a very heterogeneous response in AML patients," said Jatinder Lamba, Ph.D., the study's lead author and a researcher who holds appointments in both the College of Pharmacy and the Masonic Cancer Center, University of Minnesota. "Our latest findings lead us to believe that genetic variation in CD33 influences how AML patients' leukemic cell responds to GO."

AML is a cancer of the blood and bone marrow, and is the second most common form of leukemia in children. Though the most common type of treatment for AML is chemotherapy, Lamba says the disease remains hard to treat and newer, more effective therapies are needed.

"The overall goal of our study was to use genetic data to predict beneficial or adverse response to a specific drug, thus opening up opportunities to use this information for drug optimization to achieve maximum therapeutic efficacy and minimum toxicity. Our hope is that our research could serve as a marker of prognostic significance for clinicians to select the therapy that has the greatest odds of being effective for individual patients based on their CD33 genotype."

###

Other University of Minnesota researchers involved in the study include Leslie Mortland, M.D., from the University of Minnesota Medical School and Betsy Hirsch, Ph.D., from the Medical School and the Masonic Cancer Center, University of Minnesota.

The University of Minnesota College of Pharmacy, the only school of pharmacy in Minnesota, offers its program on the Twin Cities and Duluth campuses. Founded in 1892, the College of Pharmacy educates pharmacists and scientists and engages in research and practice to improve the health of the people of Minnesota and society. The college is part of the Academic Health Center, which is home to the University of Minnesota's six health professional schools and colleges as well as several health-related centers and institutes. Learn more at www.pharmacy.umn.edu.

The University of Minnesota Medical School, with its two campuses in the Twin Cities and Duluth, is a leading educator of the next generation of physicians. Our graduates and the school's 3,800 faculty physicians and scientists advance patient care, discover biomedical research breakthroughs with more than $180 million in sponsored research annually, and enhance health through world-class patient care for the state of Minnesota and beyond. Visit www.med.umn.edu to learn more.

Masonic Cancer Center, University of Minnesota is part of the University's Academic Health Center. It is designated by the National Cancer Institute as a Comprehensive Cancer Center. For more information about the Masonic Cancer Center, visit www.cancer.umn.edu or call 612-624-2620.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-02/uoma-uom022613.php

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San Francisco To Dublin, Ad Specialist Quantcast Opens EMEA Ops Center, Plans 100 Non-Engineering Jobs

3265v3-max-250x250Digital advertising specialist Quantcast has become the latest U.S. tech company to put down roots in Dublin. The San Francisco-headquartered company has announced the opening of a new EMEA Operations Center in the Irish city to support the "growth and expansion" of its advertising business throughout Europe, and better support existing clients in the region -- echoing a similar move by Dropbox last December, along with many others before it including Twitter, Facebook, Google, Yahoo, PayPal, LinkedIn, and Apple.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/ALA03tS82Y0/

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H.P. and LG Put WebOS on Television - NYTimes.com

Maybe the little operating system that couldn?t will gain a new life inside televisions, cars and washing machines.

Hewlett-Packard, which grabbed the WebOS mobile operating system when it bought Palm for $1.2 billion in 2010, has sold to LG Electronics the WebOS source code for an undisclosed price. In addition, what H.P. termed ?many dozens? of employees will transfer to LG, based in Seoul, South Korea. H.P. is retaining the patents and a cloud-based infrastructure for secure management of applications.

WebOS, which was released to much fanfare and technical admiration but never caught on because H.P. never made a device that caught on, will remain an open source product on which other parties can develop software, both companies said. If people do find good uses for it, it?s possible that more companies will want to use WebOS, which could benefit H.P.

Hewlett-Packard doesn?t use it in a new tablet computer it announced over the weekend. The Slate 7 uses Android.

?In the world today, patents are valuable,? said William L. Veghte, H.P.?s chief operating officer. ?We?re retaining the ability to leverage WebOS.? It seems likely, however, that H.P. will play at most a role of servicing devices on behalf of consumer companies like LG.

For LG, the product may be a way to turn televisions and other devices into hubs for a household?s computers, tablets and other connected gear. WebOS was notable for multitasking capabilities, along with a well-regarded user interface.

?We?d like to apply this technology to the next generation of smart TVs and expand it to other devices,? said Skott Ahn, LG Electronics?s president and chief technology officer. He described the operating system as having strong ?cross-platform? capabilities that would make it useful for consumers ?who have a lot more use of a ?second screen,? with things like PCs and Android.?

LG already makes personal computers and smartphones that use Google?s Android operating system. Mr. Ahn said LG had no immediate plans to make a WebOS smartphone. ?Now Android is prevailing,? he said.

Other uses for WebOS, he said, might include signs, smart cars, and home appliances. In other words, places where there are not already dominant operating systems. ?We?d like to secure a software platform across all devices,? Mr. Ahn said.

For H.P., selling these parts of Palm brings it closer to ending a bad memory. Given that H.P. never made a successful product with Palm technology, this sale most likely did not recover the purchase price or investments H.P. later made in a Palm-based smartphone and tablet or in trying to build a developer community for WebOS.

The products had their premiere in February 2011 and were killed six months later, after poor sales. H.P. made WebOS an open source product in January 2012.

H.P. just announced one of the lowest-price Android tablets. If LG is able to make a success of WebOS smart televisions and cars, its patents could become valuable, along with the applications management business.

Meg Whitman, H.P.?s chief executive, has said that smartphones remain a priority, but the company is wary of moving into a business with an entirely different distribution system of phone stores and carriers.

?If you?re not careful, you can lose a lot of money? in smartphones, Ms. Whitman said in an interview after last week?s earnings release. ?We?re still working on it.?

Source: http://bits.blogs.nytimes.com/2013/02/25/h-p-and-lg-put-webos-on-television/

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Monday, February 25, 2013

NFL Combine Live: Lane Johnson Runs 4.75 Unofficial 40-Yard Dash at 303 Pounds, Luke Joeckel Timed at 5.22

Luke Joeckel12:25 p.m.:?The official times are in and Terron Armstead still leads the way. Though he was unofficially clocked at 4.65, his official time is 4.71. Lane Johnson actually improved his time once it became official. His initial time was 4.74 and it boosted up to 4.72.

11:40 a.m.:?Lane Johnson?s second 40 matched his first at 4.75, but he improved his 10-yard split to 1.61. That?s the best of the day, and it?s significant, because that?s usually all an offensive lineman would ever be asked to run at full speed.

11:28 a.m.:?The guard that Mike Mayock is touting as the best player in the draft, Chance Warmack, ran a 5.55 40-yard dash with a 1.85 10-yard split. That time is a little disappointing, but overall it shouldn?t matter.

Menelik Watson was supposed to light up the 40, but turned in an only respectable 5.25.

11:18 a.m.:?These incredible 40 times for linemen just keep coming in now. Vinston Painter of Virginia Tech just ran a 4.87. He looked to have a lot of room to bulk up. His build looked more like a linebacker than an offensive lineman.

11:15 a.m.:?Kyle Long, Howie?s son and Chris? brother was timed at 4.93. That?s three 300-plus pound offensive linemen that have been timed under five seconds now ? Long, Lane Johnson and Terron Armstead.

Of course, these are unofficial times and the official electronic times usually come in a few ticks slower.

11:08 a.m.:?Tanner Hawkinson out of Kansas came this close?to being the second offensive lineman to run a sub-5 40. He ran a 5.00 flat 40.

Mark Jackson of Glenville State ran the slowest so far at 5.63.

Potential No. 1 overall pick Luke Joeckel just ran a 5.22. he may improve on that in his second heat.

Lane Johnson, the former quarterback and tight end just ran a 4.75 at 303 pounds. Wow.

10:50 a.m.:?South Carolina running back Marcus Lattimore is progressing from his knee injury incredibly well. He told Gil Brandt of NFL.com that he?ll begin running on Monday.

10:10 a.m.:?The linemen are going through their positional drills now and Jonathan Cooper is flashing, which is no surprise. Cooper is even higher than Alabama guard Chance Warmack on some draft boards.

Eric Fisher has been impressive, and Mike Mayock says he?s just as good as Luke Joeckel (which this NESN.com writer disagrees with).

Travis Frederick didn?t run the best 40 time (he actually ran the worst), but he?s looked much better in lineman drills.

Alabama tackle/guard D.J. Fluker is supposedly a first-round prospect, but his footwork still needs a lot of work. His future may be at guard since he has trouble kicking out against faster defensive linemen.

9:45 a.m.: It all reality, an offensive lineman won?t be asked to run 40 yards down the field (unless you?re Dan Connolly on a kick return), but a 40-yard dash does show off athleticism. The more important figure for offensive linemen are 10-yard splits. That?s the first 10 yards of a 40.

Armstead leads the way with a 1.64 10-yard split, followed by UCLA OT Jeff Baca with a 1.68. Eric Fisher?s 1.70 and Jonathan Cooper?s 1.73 look good as well. BYU OT Braden Brown and Arkansas OG Alvin Bailey finish out the top 10-yard splits with 1.74?s.

9:34 a.m.:?Terron Armstead?s second 40 time wasn?t quite as impressive, but a 4.71 at 306 pounds is still freakish athleticism.

FSU kicker Dustin Hopkins ran a 4.69 on his second 40, which is pretty insane for a kicker. You?ll rarely see a sub-5 40 for a kicker.

Jonathan Cooper ran a 5.25 on his second attempt. He?ll impress at the 3-cone drill today.

9:23 a.m.:?Terron Armstead turned in the fastest time at 4.65 unofficially and Wisconsin center Travis Frederick just ran the slowest at 5.60. His impressive beard may have been slowing him down.

9:17 a.m.:?Jonathan Cooper wasn?t able to get under five seconds on his 40, but a 5.13 is a great time for a 312-pound guard.

First-round prospect Eric Fisher just impressed with a 5.07.

9:08 a.m.:?The combine speed drills just started off with a bang. Terron Armstead of Arkansas-Pine Bluff ran an unofficial 4.65 unofficial 40-yard dash at over 300 pounds. That would set a combine record for an offensive lineman.

Arkansas punter Dylan Breeding kicked off the event with a 4.75 40 and Florida State kicker Dustin Hopkins ran a 4.81. It?s rare for special teamers to run sub-5 40s.

Virginia tackle Oday Absoushi disappointed with a 5.44 and Colorado offensive tackle David Bakhtiari, who met with the Patriots, looked smooth with a 5.01.

8 a.m. ET: The NFL scouting combine is officially upon us, and you know what that means: draft season has officially begun. The offensive linemen and tight ends will be out on display, and this is a great class for both positions.

Among the offensive linemen, Oklahoma offensive tackle Lane Johnson is supposed to test the best. He?s a former quarterback and tight end prospect who could run a 40-yard dash as low as 4.7. That would be an incredible figure for a player who?s over 6-foot-6 and 300 pounds.

UNC?s Jonathan Cooper is expected to be the most athletic guard in Indianapolis on Saturday. He?s among the best pulling guards the draft has ever seen. His speed and agility should test out very well. Some other names to watch are Alabama?s Chance Warmack, BYU?s Braden Brown, Texas A&M?s Luke Joeckel and Florida State?s Menekik Watson.

At tight end, San Diego State?s Gavin Escobar, Stanford?s Zach Ertz and Notre Dame?s Tyler Eifert are players to watch. Those are the top three players in the class and should all test out well in speed and agility drills. Some more under the radar players are Florida?s Jordan Reed, who is looked at as an Aaron Hernandez clone, and Rice?s Vance McDonald.

Stay here for the news and analysis coming out of Day 3 of the combine. We?ll send out the best 40 times, most impressive performances and all the biggest news.

Source: http://nesn.com/2013/02/nfl-combine-live-lane-johnson-gavin-escobar-among-offensive-linemen-tights-ends-expected-to-shine/

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Sunday, February 24, 2013

For some Indians, latest bombing brings sense of d?j? vu

Suleman Sultan, a survivor of a blast almost identical to the recent attack in Hyderabad, says the government's response is following the same old script.?

By Raksha Kumar,?Contributor / February 24, 2013

Hindu priests lift up an oil lamp as they perform an evening prayer ceremony for the victims of the explosions which took place in Hyderabad on Thursday, on the banks of the river Ganges in the northern Indian city of Allahabad February 24.

Jitendra Prakash/Reuters

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Indian Prime Minister Manmohan Singh visited today the southern city of Hyderabad, the scene of a double bombing on Thursday.?The deadly attacks echoed another double blast six year ago here, as well as a long string of terrorist incidents around the country, most of which remain unresolved and have upended the lives of ordinary people.?

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Thursday's bombs ripped through the crowded?Dilsukhnagar area in quick succession killing 16 people and injuring more than 120. The city, including the volatile Old City area, has been peaceful since the blasts.

?I am happy that people of Hyderabad have refused to be provoked by this nefarious incident,? said Prime Minister Singh while speaking to the media.?

The plaudits, however, are not flowing as freely in the other direction, with Indian citizens and the media expressing weariness with the repetitive urban bombings over the years and the government's inability to solve and stop them.?

While in Hyderabad, Singh visited a hospital to meet with survivors of the blasts.?He had announced earlier a?compensation of 200,000 rupees ($3,700) to relatives of the deceased and 50,000 rupees?($900) to those severely injured in the attacks from the Prime Minister?s Relief Fund. The chief minister of the state of Andhra Pradesh, where Hyderabad is located, also announced additional compensation of 600,000 rupees ($11,900) each for the families of those killed in the blast, and assured that the government would bear the expense of the treatment of those who were injured.

This is d?j? vu for Suleman Sultan, a victim of one of the 2007 bombs that went off in a snack bar in Hyderabad.

?They gave me 200,000 rupees [$3,700] and took care of my treatment for five months in a hospital,? says Mr. Sultan. ?I guess, that is all the Indian state can offer its citizen, right?? he smiled a painful smile. Sultan's lower body is paralyzed after shrapnel from the bomb damaged his spinal cord. He had returned from Australia a few days before the 2007 blast and was very happy to have landed a job as a telecom engineer. He could not take that job and the mostly immobilized 28-year-old now must be supported by his father and younger brother.?

Sultan used to be edgy and irritable immediately after his surgery, he snapped at many a reporter, he confesses. He has mellowed down, says his mother. ?So much so, that my talkative child remains silent most of the time,? she adds.

It is customary for Indian authorities to offer compensation to high-profile victims of crime, disasters, or terrorism. But the money often cannot repair the damage done, and attention to victims and their cases wanes quickly.?

Like Thursday's attacks, the two bombs in 2007 ripped through crowded civilian areas?? an amusement park and a snack bar?? within a span of five minutes.?The explosive materials (ammonium nitrate and RDX ) used were the same in 2007 as the recent blasts.

Even though several people were arrested immediately after the blasts in 2007, no one has been convicted yet. The slow pace of investigation has frustrated the victims.

?Now you will hear the police saying similar things they did at that point. The conspiracy theories, the arrests, the acquittals will all take place and there will be more blasts again in a few years,? Sultan says.

Sultan?s prediction saw some truth on Sunday as newspaper reports pointed fingers at several possible suspected terrorist groups, notably the Indian Mujahideen, a banned terrorist organization. According to unnamed investigators in several newspapers, Indian Mujahideen?s co-founder, Yasin Bhaktal, is the main suspect. Mr. Bhaktal has been named almost every year in a terror attack in the country since 2007, but has always managed to escape.

"We have footage from the camera [at the blast site] which we are analyzing," said Hyderabad Commissioner of Police Anurag Sharma while speaking to media on Saturday. "We have not arrested anyone in this case. We are examining all types of evidences," he added.

?We are all Muslims, why don?t they understand that?? asked Sultan, as the group that is suspected of planting the bombs in 2007 was a Bangladesh-based militant group. As for the government, he asks: ?We want to live peacefully, and if we expect that from our elected representatives what is wrong in that??

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/NbLK_IcNCMk/For-some-Indians-latest-bombing-brings-sense-of-deja-vu

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Saturday, February 23, 2013

Lindsay Lohan Chewed to Pieces in Pitbull Lawsuit

LOS ANGELES (TheWrap.com) - As it turns out, Lindsay Lohan doesn't have much luck as a plaintiff in legal proceedings either.

Troubled "Liz & Dick" actress Lohan, who has experienced more than her share of legal woes in recent years, was shot down Thursday in her lawsuit against Pitbull, Ne-Yo and Afrojack over the 2011 song "Give Me Everything."

Lohan had sued the trio, along with others, under New York Civil Rights Law, claiming that the song made "disparaging and defamatory statements" about Lohan, violated her privacy, and used her name for advertising purposes without authorization.

Oh, and she also claimed that the tune caused her "tremendous emotional distress."

Specifically, Lohan took issue with the lyrics, "So, I'm tiptoein', to keep flowin'/I got it locked up like Lindsay Lohan."

However, Lohan's claims went down in flames in U.S. District Court in New York on Thursday, as Judge Denis R. Hurley granted the defendants' motion to dismiss and tossed out Lohan's complaint.

In his ruling, Hurley found that the song, as a protected work of art under the First Amendment, doesn't violate the New York Civil Rights Law.

The judge also dismissed Lohan's claim that the songwriters used her name for advertising or purposes or trade.

"Even if the Court were to conclude that plaintiff had sufficiently alleged that her name was used in the Song for purposes of advertising or trade, the isolated nature of the use of her name would, in and of itself, prove fatal to her New York Civil Rights Law claim," Hurley found.

As for the claim of emotional distress? Yeah, that didn't fly either, with Hurley ruling, "even if the defendants used plaintiff's name in one line of the Song without her consent, such conduct is insufficient to meet the threshold for extreme and outrageous conduct necessary to sustain a claim for intentional infliction of emotional distress."

On the plus side for Lohan, the judge decided not to impose sanctions on the actress, as the defendants had requested.

In her complaint, Lohan asked for a permanent injunction preventing any further distribution of the song, plus an injunction ordering the defendants to surrender all existing copies of the song to Lohan.

Naturally, she was also asking for an accounting of the profits that the song had generated for the defendants to date, and "compensatory damages in an amount to be determined in the Court."

Looks like she's the one who hit a bum note, as far as the justice system is concerned.

(Pamela Chelin contributed to this report)

Source: http://news.yahoo.com/lindsay-lohan-chewed-pieces-pitbull-lawsuit-175608266.html

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International Conference on Somalia, London

Somalia - somalia Order Report

Publisher Council on Foreign Relations Press

Release Date March 2010

Price $10.00

60 pages
ISBN 978-0-87609-473-0
Council Special Report No. 52

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Overview


This report is sponsored by CFR's Center for Preventive Action.

Even among failed states--those countries unable to exercise authority over their territory and provide the most basic services to their people--Somalia stands apart. A country of some nine million, it has lacked a central government since the fall of Mohamed Siad Barre's regime in 1991. Poverty and insecurity are endemic. Less than 40 percent of Somalis are literate, more than one in ten children dies before turning five, and a person born in Somalia today cannot assume with any confidence that he or she will reach the age of fifty.

Failed states provide fertile ground for terrorism, drug trafficking, and a host of other ills that threaten to spill beyond their borders. Somalia is thus a problem not just for Somalis but for the United States and the world. In particular, the specter of Somalia's providing a sanctuary for al-Qaeda has become an important concern, and piracy off Somalia's coast, which affects vital international shipping lanes, remains a menace.

In this Council Special Report, Bronwyn E. Bruton proposes a strategy to combat terrorism and promote development and stability in Somalia. She first outlines the recent political history involving the Transitional Federal Government (TFG) formed in 2004 and its Islamist opponents, chiefly the Shabaab, which has declared allegiance to al-Qaeda. She then analyzes U.S. interests in the country, including counterterrorism, piracy, and humanitarian concerns, as well as the prospect of broader regional instability.

Bruton argues that the current U.S. policy of supporting the TFG is proving ineffective and costly. The TFG is unable to improve security, deliver basic services, or move toward an agreement with Somalia's clans and opposition groups that would provide a stronger basis for governance. She also cites flaws in two alternative policies--a reinforced international military intervention to bolster the TFG or an offshore approach that seeks to contain terrorist threats with missiles and drones.

Instead, Bruton advances a strategy of "constructive disengagement." Notably, this calls for the United States to signal that it will accept an Islamist authority in Somalia--including the Shabaab--as long as it does not impede international humanitarian activities and refrains from both regional aggression and support for international jihad. As regards terrorism, the report recommends continued airstrikes to target al-Qaeda and other foreign terrorists while taking care to minimize civilian casualties. It argues for a decentralized approach to distributing U.S. foreign aid that works with existing local authorities and does not seek to build formal institutions. And the report counsels against an aggressive military response to piracy, making the case instead for initiatives to mobilize Somalis themselves against pirates.

Somalia: A New Approach takes on one of today's most vexing foreign policy challenges, offering concise analysis and thoughtful recommendations grounded in a realistic assessment of U.S. and international interests and capabilities. It is an important contribution to the debate over how to proceed in this most failed of states.

?

Bronwyn E. Bruton, a democracy and governance specialist with extensive experience in Africa, was a 2008-2009 international affairs fellow in residence at the Council on Foreign Relations. She was born in Swaziland and spent most of her childhood in Botswana. Prior to her fellowship appointment, Bronwyn spent three years at the National Endowment for Democracy, where she managed a $7 million portfolio of grants to local and international nongovernmental organizations in east and southern Africa (priority countries included Somalia, Ethiopia, Eritrea, Uganda, Kenya, Zimbabwe, and Sudan). Bruton has also served as a program manager on the Africa team of the U.S. Agency for International Development's Office of Transition Initiatives, and as a policy analyst on the international affairs and trade team of the Government Accountability Office. She holds an MPP, with honors, from the University of California at Los Angeles.

?

Source: http://feeds.cfr.org/~r/world_events/~3/XqYR5hS3vVk/p21421

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Friday, February 22, 2013

Qualcomm announces global LTE solution for mobile devices

Android Central

Let's face it, LTE is a mess. The different flavors found all around the world causes issues not just for consumers -- try traveling abroad and getting LTE -- but also for OEM's who actually want to put LTE into their devices. What if, what if one device could pick up LTE wherever you happened to travel? 

Enter Qualcomm, and the announcement of the RF360, which is hailed as the worlds first global LTE compatible front end solution. We're not going to see anything carrying it anytime soon, Qualcomm says they expect the first devices to be available in the second half of 2013. But, that's still not all that far away. Exciting times for sure, and the full release can be found after the break. 

Source: Qualcomm

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/FymFqMWn7e4/story01.htm

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California water board urges lawmakers to act on nitrate contamination in drinking water

A new report from the state water board calls for the Legislature to enact new fees to pay for measures designed to clean up nitrate-contaminated groundwater, especially in major agricultural areas such as the Salinas Valley.

The report, issued Wednesday, includes 15 recommendations to address a range of water issues. Among the recommendations: providing clean drinking water, especially for small, disadvantaged communities that rely on contaminated groundwater linked to heavy fertilizer use.

An estimated 2.6 million people, many from some of the poorest communities in the state, rely on groundwater for drinking water in the Salinas and San Joaquin valleys, according to an earlier report by UC Davis.

Nitrate-contaminated drinking water has been linked to birth defects, cancer and other diseases.

Wednesday's report, issued in response to state legislation on nitrate contamination approved in 2008, urges lawmakers to protect groundwater sources from further contamination, monitor and manage contaminated groundwater, and track and report nitrogen fertilizing materials.

But the report said its most critical recommendation is to create a reliable, stable funding source to "ensure all Californians, including those in (disadvantaged communities), have access to safe drinking water."

New funding sources proposed in the report include a point-of-sale fee on agricultural commodities, a fee on nitrogen fertilizing materials or a water use fee.

Clean

Water Action, a national advocacy organization, praised the board's recommendations, particularly the call for a statewide fertilizer fee. The group pointed to the UC Davis report, which estimated nitrate pollution costs taxpayers as much as $36 million per year to provide drinking water to communities in the Salinas Valley and southern San Joaquin Valley affected by polluted agricultural runoff.

The organization said Monterey County's ag industry brings in more than $3 billion per year, while small rural communities are left to deal with the cost of unsafe water.

However, Monterey County Farm Bureau Executive Director Norm Groot said additional taxes or fees, and expensive regulations, would place an unwise burden on an ag industry already struggling in recent years.

Groot said he hadn't fully analyzed the report and its recommendations, but said local farmers had been "bracing" for a fertilizer fee. He said he would need more details about the size and purpose of any proposed fees, but said: "I doubt ag can afford another tax."

The report suggested the state water board and Regional Water Quality Control Board use their authority to order those responsible for nitrate contamination to provide replacement water for affected communities. It called for the Legislature to set up a regulatory framework for providing safe drinking water and to develop, operate and manage new systems for disadvantaged communities.

The water boards would be required to define and identify areas at high risk of nitrate contamination to prioritize regulatory oversight and assistance in the areas.

New and improved groundwater monitoring programs are needed, according to the report, and the Legislature should require that well owners and small unregulated water systems in high-risk areas be identified and notified.

The water boards and state Food and Agriculture officials should convene a task force to work on a nitrogen tracking system, the report recommended, and a panel of experts should be convened to assess existing ag nitrate control programs and suggest improvements as needed.

The state board relied on the UC Davis report as a foundation for its findings and recommendations, and included input from an interagency task force that included representatives from the state Departments of Public Health, Food and Agriculture and Pesticide Regulation, as well as the state's Environmental Protection Agency and local environmental health agencies.

The UC Davis report's major findings include:

? Nitrate problems will likely worsen for decades after infiltrating the Salinas Valley and Tulare Lake Basin aquifers for more than a half century.

? Ag fertilizers and animal wastes applied to cropland are by far the largest regional sources of nitrate in groundwater.

? Many small communities can't afford safe drinking water treatment.

? The most promising revenue source is a fertilizer fee.

? A statewide data collection effort is needed.

The report was released as Assemblyman Luis Alejo, D-Watsonville, announced he and several colleagues had introduced a package of nine bills aimed at addressing the state's "drinking water crisis." Alejo's bill, AB 1, is called the Salinas Valley Clean Water Funding Bill.

Jim Johnson can be reached at 753-6753 or jjohnson@montereyherald.

com.

Source: http://www.montereyherald.com/ci_22632979/california-water-board-urges-lawmakers-act-nitrate-contamination?source=rss_viewed

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TI-84 Plus C Silver Edition Review: Math in Color!

The new TI-84 Plus C Silver Edition isn't the first color-screen graphing calculator. It isn't even TI's first color graphing calculator, a distinction claimed by the TI-Nspire CX and its sibling the TI-Nspire CX CAS. However, the TI-84+CSE, as we're abbreviating it, is a major milestone in the 17-year-old TI-83 and TI-84 Plus family of calculators. Although it retains the look and feel of the TI-84 Plus operating system, and keeps the familiar case shape and key layout, the outstanding feature of the TI-84+CSE is a bright, glossy color LCD screen. No longer will math and programs need to squeeze into 96 by 64 monochrome pixels; the new screen is 320x240 and can display 65,000 different colors. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/jeylxtDWcJM/ti+84-plus-c-silver-edition-review-math-in-color

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